VEGFR-2-IN-27

VEGFR-2-IN-27

• CAS Number: 2439096-14-5
• UNSPSC Description: VEGFR-2-IN-27 (compound 7a) is a highly potent VEGFR-2 inhibitor with an IC50 value of 14.8 nM. VEGFR-2-IN-27 can be used for researching anticancer[1].
• Target Antigen: VEGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/vegfr-2-in-27.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=NC(OC2=CC=C(NC(NC3=CC=CC(C)=C3)=O)C(F)=C2)=C4C=CC=CC4=N1)OCC
• Molecular Weight: 460.46
• References & Citations: [1]Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported