Anticancer agent 69

CAT: 0804-HY-146170Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146170Size:1 Each
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Description
Anticancer agent 69 (Compound 34), a potent and selective anticancer agent, potently and selectively inhibits human prostate cancer cell line PC3 (IC50=26 nM) . Anticancer agent 69 increases ROS level, down-regulates EGFR and induces apoptosis[1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Apoptosis; EGFR; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; NF-κB; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-69.html
Solubility
10 mM in DMSO
Smiles
[H]/C(C1=CC=CC=N1)=N\NC2=NC(SCCC)=NC3=C2N=NN3CCCCCC
Molecular Formula
C19H26N8S
Molecular Weight
398.53
References & Citations
[1]Chenhao Xu, et al. Novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing hydrazone fragment as potent and selective anticancer agents. Bioorg Chem. 2020 Dec;105:104424.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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