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Aminooxy-PEG2-BCN

CAT: 0804-HY-145593Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145593Size:1 Each
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Description
Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Aminooxy-PEG2-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
CAS Number
2253965-14-7
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aminooxy-peg2-bcn.html
Purity
50
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCCNC(CON)=O)OCC1C2CCC#CCCC12
Molecular Formula
C19H31N3O6
Molecular Weight
397.47
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker

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