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SZ-015268

CAT: 0804-HY-145389Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-145389Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SZ-015268 is a CDK7 inhibitor with an IC50 of 23.56 nM. SZ-015268 has extremely significant anti-tumor advantages. SZ-015268 inhibits HCC70, OVCAR-3, HCT116 and HCC1806 cells proliferation with IC50s of 33, 80.56, 12.53, and 61.55 nM, respectively[1].
CAS Number
2654003-68-4
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sz-015268.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CN=C(C(NC(CC2)CCN2C(O[C@@H](CC3)CN3C(/C=C/CN(C)C)=O)=O)=N4)N1N=C4C)C
Molecular Formula
C25H38N8O3
Molecular Weight
498.62
References & Citations
[1]Heterocyclic compound, and pharmaceutical composition thereof, preparation method therefor, intermediate thereof and application thereof. WO2021121390A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7

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