Heterobivalent ligand-1

• UNSPSC Description:

  Heterobivalent ligand-1 (compound 26) is a heterobivalent ligand for the Adenosine A 2A-dopamine D 2 receptor heteromer (KDB1 A2AR=2.1 nM, KDB1 D2R= 0.13 nM)[1].

• Target Antigen:

  Adenosine Receptor; Dopamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/heterobivalent-ligand-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CN(CC(OC)=O)CC(NCCOCCOCCOCCOCCOCCNC(COC1=CC=C(CCCN2N=CC3=C2N=C(N)N4C3=NC(C5=CC=CO5)=N4)C=C1)=O)=O)NCCOCCOCCOCCOCCOCCNC(CCC(NC6=CC=C(CCN7CN(C8=CC=CC=C8)C9(CCN(CCCC(C%10=CC=C(F)C=C%10)=O)CC9)C7=O)C=C6)=O)=O

• Molecular Weight:

  1741.95

• References & Citations:

  [1]Pulido D, et al. Heterobivalent Ligand for the Adenosine A2A-Dopamine D2 Receptor Heteromer. J Med Chem. 2022;65(1):616-632.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2888568-58-7