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CALR ligand 1

CAT: 0931-T211234-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211234-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3055854-78-6
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand with anti-tumor activity against triple-negative breast cancer (TNBC) cells, exhibiting an IC50 of 0.1 μM. It induces intracellular calcium overload, leading to apoptosis in TNBC cells, making it a promising candidate for further research on triple-negative breast cancer.
Smiles
O=C(NC1=NNC2=NC=C(C=C21)C=3C=CC(=CC3)S(=O)(=O)C(C)C)CCl
Molecular Formula
C17H17ClN4O3S
Molecular Weight
392.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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