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LY 222306

CAT: 0804-HY-14522Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-14522Size:1 Each
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Description
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
CAS Number
154446-98-7
UNSPSC
12352005
Target
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/LY_222306.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(NCC(CCC(O3)=CC=C3C(N[C@@H](CCC(O)=O)C(O)=O)=O)C2)N=C(N)N1
Molecular Formula
C19H23N5O7
Molecular Weight
433.42
References & Citations
[1]Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54 (4) :1021-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
MBS3845564-01LY 222306
A21133-5LY 222306 5mg
A21133-10LY 222306 10mg
A21133-100LY 222306 100mg
A21133-50LY 222306 50mg
A21133-25LY 222306 25mg
A21133-1LY 222306 1mg

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