Anticancer agent 40

• Description :

  Anticancer agent 40 (compound 3e) is a potent anticancer agent. Anticancer agent 40 shows anticancer activities with IC50s of 0.94, 0.98, 0.96, 0.95, 2.13 nM for SKBR-3, SKOV-3, PC-3, U-87, HDF cells, respectively[1].

• UNSPSC :

  12352005

• Target :

  Microtubule/Tubulin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/anticancer-agent-40.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C(OC/C=C/C)C(C=C3)=O)=O

• Molecular Formula :

  C25H29NO6

• Molecular Weight :

  439.50

• References & Citations :

  [1]Pyta K, et al. Regioselective approach to colchiceine tropolone ring functionalization at C (9) and C (10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :597-605.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2760658-33-9]