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FGFR4-IN-9

CAT: 0804-HY-144759Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144759Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR4-IN-9 (Compound 6O) is a selective FGFR4 inhibitor with an IC50 of 75.3 nM. FGFR4-IN-9 effectively inhibits both the growth and angiogenesis of HCC[1].
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr4-in-9.html
Solubility
10 mM in DMSO
Smiles
C=CC(NC1=CC(F)=CC(Cl)=C1NC2=NC(C)=C(C(C)=N2)OCC3=C(C(OC)=CC(OC)=C3F)F)=O
Molecular Formula
C24H22ClF3N4O4
Molecular Weight
522.90
References & Citations
[1]Chaudhary CL, et al. 6-Amino-2,4,5-trimethylpyridin-3-ol and 2-amino-4,6-dimethylpyrimidin-5-ol derivatives as selective fibroblast growth factor receptor 4 inhibitors: design, synthesis, molecular docking, and anti-hepatocellular carcinoma efficacy evaluation. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :844-856.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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