Mpro/PLpro-IN-1

CAT:
804-HY-144648
Size:
1 Each
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Mpro/PLpro-IN-1 - image 1

Mpro/PLpro-IN-1

  • Description :

    Mpro/PLpro-IN-1 (Compound 29) is a potent inhibitor of Mpro/PLpro. Mpro/PLpro-IN-1 is a dual acting SARS-CoV-2 proteases inhibitor featuring micromolar inhibitory potency versus Mpro (IC50 = 1.72 μM) and submicromolar potency versus PLpro (IC50 = 0.67 μM) [1].
  • UNSPSC :

    12352005
  • Target :

    SARS-CoV
  • Type :

    Reference compound
  • Related Pathways :

    Anti-infection
  • Applications :

    COVID-19-anti-virus
  • Field of Research :

    Infection
  • Assay Protocol :

    https://www.medchemexpress.com/mpro-plpro-in-1.html
  • Solubility :

    10 mM in DMSO
  • Smiles :

    C=CC[C@H](NC(CCl)=O)C(N[C@@H](CC1=CNC2=C1C=CC=C2)C(NCC3=CC=CC=C3)=O)=O
  • Molecular Formula :

    C25H27ClN4O3
  • Molecular Weight :

    466.96
  • References & Citations :

    [1]Di Sarno V, et al. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization. Eur J Med Chem. 2021;226:113863.
  • Shipping Conditions :

    Room temperature
  • Scientific Category :

    Reference compound1
  • Clinical Information :

    No Development Reported
  • CAS Number :

    [2766185-78-6]