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Anticancer agent 28

CAT: 0804-HY-144232Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144232Size:1 Each
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Description
Anticancer agent 28 shows good antitumor activity in H22 allogeneic mice in vivo. Anticancer agent 28 has inhibitory potency in K562 cells of 50 times than oridonin, and its IC50 value is 0.09 μM.
CAS Number
2768083-57-2
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-28.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CCC[C@]2(CO3)C1[C@H](O)[C@]3(O)[C@]4(C5=O)C2CC[C@@H](C5=C)[C@H]4OC(/C=C/C6=CC=NC=C6)=O
Molecular Formula
C28H33NO6
Molecular Weight
479.56
References & Citations
[1]Liu J, et al. Identification of new potent anticancer derivatives through simplifying the core structure and modification on their 14- hydroxyl group from oridonin. Eur J Med Chem. 2022 Mar 5;231:114155.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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