Anticancer agent 28

• Description:

  Anticancer agent 28 shows good antitumor activity in H22 allogeneic mice in vivo. Anticancer agent 28 has inhibitory potency in K562 cells of 50 times than oridonin, and its IC50 value is 0.09 μM.

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-28.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)CCC[C@]2(CO3)C1[C@H](O)[C@]3(O)[C@]4(C5=O)C2CC[C@@H](C5=C)[C@H]4OC(/C=C/C6=CC=NC=C6)=O

• Molecular Formula:

  C28H33NO6

• Molecular Weight:

  479.56

• References & Citations:

  [1]Liu J, et al. Identification of new potent anticancer derivatives through simplifying the core structure and modification on their 14- hydroxyl group from oridonin. Eur J Med Chem. 2022 Mar 5;231:114155.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2768083-57-2]