NLRP3/AIM2-IN-2
CAT:
804-HY-144223-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NLRP3/AIM2-IN-2
- CAS Number: 791840-86-3
- UNSPSC Description: NLRP3/aim2-in-2 (compound 8) is a new potent inhibitor with different species-specific effects on NLRP3 and AIM2 inflammasome dependent cell death. Its IC 50 value is 0.2392 ± 0.0233 μ M。
- Target Antigen: AIM2; NOD-like Receptor (NLR)
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/nlrp3-aim2-in-2.html
- Solubility: DMSO : 125 mg/mL (ultrasonic)
- Smiles: O=C(NC1=CC=CC(O)=C1)CC2=CC=C(OC)C=C2
- Molecular Weight: 257.28
- References & Citations: [1]Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported