RET-IN-12

• UNSPSC Description:

  RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively[1].

• Target Antigen:

  RET

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ret-in-12.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC(NC(CC2=CC=C(C3=CN=C4C=C(C(OC)=CC4=C3)OC)N=C2)=O)=CC(C(F)(F)F)=C1)NCCN(C)C

• Molecular Weight:

  581.59

• References & Citations:

  [1]ZHANG YANG (CN), et al. PHENYL BISAMIDE COMPOUND. Patent WO2021164741A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2684252-55-7