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RET-IN-12

CAT: 0804-HY-144030Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144030Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET (WT) and RET (V804M), respectively[1].
CAS Number
2684252-55-7
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ret-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(NC(CC2=CC=C(C3=CN=C4C=C(C(OC)=CC4=C3)OC)N=C2)=O)=CC(C(F)(F)F)=C1)NCCN(C)C
Molecular Formula
C30H30F3N5O4
Molecular Weight
581.59
References & Citations
[1]ZHANG YANG (CN), et al. PHENYL BISAMIDE COMPOUND. Patent WO2021164741A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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T64103-01RET-IN-12
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