RSV/IAV-IN-3
CAT:
804-HY-143494
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RSV/IAV-IN-3
- CAS Number: 2395007-81-3
- UNSPSC Description: RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC50 values of 2.92 µM and 1.90 µM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC50 values of 3.25 µM and 1.50 µM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC50 of 3.89 µM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage[1].
- Target Antigen: Influenza Virus; RSV
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/rsv-iav-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=CC=CC=C1OCC)CSC2=CNC3=C2C=CC(OC)=C3Br
- Molecular Weight: 435.33
- References & Citations: [1]Guo-Ning Zhang, et al. Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A. Eur J Med Chem. 2020 Jan 15;186:111861.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported