IAV-IN-3

IAV-IN-3

• CAS Number: 3049492-11-4
• UNSPSC Description: IAV-IN-3 (Compound (R,S)-16s) is an anti-influenza A virus (IAV) agent (EC50 = 0.134 μM) with weak cytotoxicity (CC50 = 15.35 μM for MDCK cells). IAV-IN-3 inhibits IAV polymerase with an IC50 of 0.045 μM[1].
• Target Antigen: Influenza Virus
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/iav-in-3.html
• Smiles: O=C1N2[C@H](CCC2)CN([C@H]3C(C=CC(F)=C4F)=C4CSC5=C3C=CC=C5)N(C1=C6O)C=CC6=O
• Molecular Weight: 481.51
• References & Citations: [1]Zhang L, et al. Design and synthesis of 7-membered lactam fused hydroxypyridinones as potent metal binding pharmacophores (MBPs) for inhibiting influenza virus PAN endonuclease. Eur J Med Chem. 2024 Jul 1;276:116639.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported