RSV-IN-5

• UNSPSC Description:

  RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM)[1].

• Target Antigen:

  RSV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/rsv-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1C2=CC(N3CC[C@@H](C3)N)=NC4=CC([C@@]5([H])N(CCCC5)C(C6=CC(C)=CC=C6OCCCC1)=O)=NN24

• Molecular Weight:

  503.64

• References & Citations:

  [1]Toru Yamaguchi-Sasaki, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2415018-86-7