SARS-CoV-IN-4

• UNSPSC Description:

  SARS-CoV-IN-4 (compound 13) is a potent and specific inhibitor of SARS-CoV nsp14 N7-methyltransferase, with an IC50 of 0.6 μM (SARS-CoV nsp14)[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]([C@@H]1O)[C@@](N2C3=NC=NC(N)=C3N=C2)([H])O[C@@H]1CN(S(=O)(C4=CC([N+]([O-])=O)=C(C=C4)Cl)=O)CCO[C@H]5[C@](O[C@@H]([C@H]5O)CO)([H])N6C7=NC=NC(N)=C7N=C6

• Molecular Weight:

  779.14

• References & Citations:

  [1]Ahmed-Belkacem R, et al. Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase. Eur J Med Chem. 2020 Sep 1;201:112557.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2445585-37-3