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SARS-CoV-IN-4

CAT: 0804-HY-143467Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143467Size:1 Each
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Description
SARS-CoV-IN-4 (compound 13) is a potent and specific inhibitor of SARS-CoV nsp14 N7-methyltransferase, with an IC50 of 0.6 μM (SARS-CoV nsp14) [1].
CAS Number
2445585-37-3
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-in-4.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@@H]1O)[C@@](N2C3=NC=NC(N)=C3N=C2)([H])O[C@@H]1CN(S(=O)(C4=CC([N+]([O-])=O)=C(C=C4)Cl)=O)CCO[C@H]5[C@](O[C@@H]([C@H]5O)CO)([H])N6C7=NC=NC(N)=C7N=C6
Molecular Formula
C28H31ClN12O11S
Molecular Weight
779.14
References & Citations
[1]Ahmed-Belkacem R, et al. Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase. Eur J Med Chem. 2020 Sep 1;201:112557.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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