SARS-CoV-2 nsp13-IN-4

• CAS Number:

  923140-39-0

• UNSPSC Description:

  SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sars-cov-2-nsp13-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=NC2=NC(C3=CC=C(C=C3)NC(C4=CC=CC(Br)=C4)=O)=CN2C=C1

• Molecular Weight:

  407.26

• References & Citations:

  [1]Aliakbar Khalili Yazdi, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported