SARS-CoV-2 nsp13-IN-4

SARS-CoV-2 nsp13-IN-4

• CAS Number: 923140-39-0
• UNSPSC Description: SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-nsp13-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=NC2=NC(C3=CC=C(C=C3)NC(C4=CC=CC(Br)=C4)=O)=CN2C=C1
• Molecular Weight: 407.26
• References & Citations: [1]Aliakbar Khalili Yazdi, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported