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CK2 inhibitor 3

CAT: 0804-HY-143461Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-143461Size:1 Each
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Description
CK2 inhibitor 3 is a potent CK2 inhibitor with IC50 value of 280 nM. CK2 inhibitor 3 inhibits endocellular CK2, significantly affects viability of tumour cells and shows remarkable selectivity on a panel of 320 kinases[1].
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck2-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(/C=C(C(NC2=NN=C(S2)Br)=O)\C#N)=CC=C1O
Molecular Formula
C13H9BrN4O3S
Molecular Weight
381.20
References & Citations
[1]Dalle Vedove A, Zonta F, Zanforlin E, et al. A novel class of selective CK2 inhibitors targeting its open hinge conformation. Eur J Med Chem. 2020;195:112267.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2

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