CK2-IN-3

• Description :

  CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’) . CK2-IN-3 can be used in the research of cancers[1].

• UNSPSC :

  12352005

• Target :

  Casein Kinase

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Stem Cell/Wnt

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ck2-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C1=CC=C(C2=C3N=C(N(C(OC(C)(C)C)=O)CCOCCO)C=CN3N=C2)C=C1O

• Molecular Formula :

  C22H26N4O7

• Molecular Weight :

  458.46

• References & Citations :

  [1]Andreas Krämer, et al. Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Eur J Med Chem. 2020 Dec 15;208:112770.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CK2

• CAS Number :

  [2969205-85-2]