CK2-IN-3

• UNSPSC Description:

  CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’). CK2-IN-3 can be used in the research of cancers[1].

• Target Antigen:

  Casein Kinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ck2-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)C1=CC=C(C2=C3N=C(N(C(OC(C)(C)C)=O)CCOCCO)C=CN3N=C2)C=C1O

• Molecular Weight:

  458.46

• References & Citations:

  [1]Andreas Krämer, et al. Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Eur J Med Chem. 2020 Dec 15;208:112770.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2969205-85-2