CK2-IN-3

CAT: 0804-HY-151382Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-151382Size:1 Each
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Description
CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’) . CK2-IN-3 can be used in the research of cancers[1].
CAS Number
[2969205-85-2]
UNSPSC
12352005
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck2-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(C2=C3N=C(N(C(OC(C)(C)C)=O)CCOCCO)C=CN3N=C2)C=C1O
Molecular Formula
C22H26N4O7
Molecular Weight
458.46
References & Citations
[1]Andreas Krämer, et al. Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Eur J Med Chem. 2020 Dec 15;208:112770.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2

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