CK2-IN-7

• Description:

  CK2-IN-7 (compound 2) is an inhibitor of casein kinase 2 (CK2) . CK2-IN-7 shows synergistic effect with structurally distinct CK2 chemical probe: SGC-CK2-1, against cancer[1].

• UNSPSC:

  12352005

• Target:

  Casein Kinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ck2-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C2C(N=C(C3=NC=NC=C32)NCC4=CC=CC=C4)=C1)O

• Molecular Formula:

  C19H14N4O2

• Molecular Weight:

  330.34

• References & Citations:

  [1]Davis-Gilbert ZW, et al. Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2. ACS Med Chem Lett. 2023 Mar 14;14 (4) :432-441.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2825012-70-0]