SB 271046

CAT: 0804-HY-14336Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-14336Size:1 Each
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Description
SB 271046 is a potent, selective and orally active 5-HT6 receptor antagonist with a pKi of 8.92-9.09. SB 271046 show >200-fold selective for the 5-HT6 receptor over other receptors, binding sites and ion channels. SB 271046 has anticonvulsant activity[1].
CAS Number
[209481-20-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-271046.html
Solubility
10 mM in DMSO
Smiles
O=S(NC1=CC=C(C(N2CCNCC2)=C1)OC)(C3=C(C)C4=C(C=CC(Cl)=C4)S3)=O
Molecular Formula
C20H22ClN3O3S2
Molecular Weight
451.99
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]C Routledge, et al. Characterization of SB-271046: a potent, selective and orally active 5-HT (6) receptor antagonist. Br J Pharmacol. 2000 Aug;130 (7) :1606-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor; MUC2

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Alternative Products

CatalogName
MBS130968-01SB-271046
MBS5750009SB 271046 hydrochloride
A11573-25SB 271046 Hydrochloride 25mg
A11573-50SB 271046 Hydrochloride 50mg
A11573-100SB 271046 Hydrochloride 100mg
A11573-5SB 271046 Hydrochloride 5mg
A11573-10SB 271046 Hydrochloride 10mg
A11573-10mM-DSB 271046 Hydrochloride 10mM * 1mL in DMSO

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