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19 (S) -HETE

CAT: 0804-HY-142972Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-142972Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
19 (S) -HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19 (S) -HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19 (S) -HETE inhibits platelet activation and relaxation of vessels[1].
CAS Number
115461-40-0
UNSPSC
12352211
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/19-s-hete.html
Solubility
10 mM in DMSO
Smiles
C[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
References & Citations
[1]Tunaru S, et al. Arachidonic Acid Metabolite 19 (S) -HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. PLoS One. 2016 Sep 23;11 (9) :e0163633.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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