19 (S) -HETE

• Description:

  19 (S) -HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19 (S) -HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC50 value of 567 nM. 19 (S) -HETE inhibits platelet activation and relaxation of vessels[1].

• UNSPSC:

  12352211

• Target:

  Prostaglandin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/19-s-hete.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O

• Molecular Formula:

  C20H32O3

• Molecular Weight:

  320.47

• References & Citations:

  [1]Tunaru S, et al. Arachidonic Acid Metabolite 19 (S) -HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. PLoS One. 2016 Sep 23;11 (9) :e0163633.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [115461-40-0]