PI3Kδ-IN-9

• UNSPSC Description:

  PI3Kδ-IN-9 is a selective PI3Kδ inhibitor with an IC50 value of 3.8 nM.

• Target Antigen:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pi3kδ-in-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@@](C)(NCC(C)(F)C)C2=CC(C3=C4N=C(C5=CN=C(C)N=C5)N(CC)C4=NC=N3)=CN=C2N1

• Molecular Weight:

  475.52

• References & Citations:

  [1]Methot JL, et al. Optimization of Versatile Oxindoles as Selective PI3Kδ Inhibitors. ACS Med Chem Lett. 2020 Nov 19;11(12):2461-2469.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2135922-40-4