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PI3Kδ-IN-9

CAT: 0804-HY-142646Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142646Size:1 Each
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Description
PI3Kδ-IN-9 is a selective PI3Kδ inhibitor with an IC50 value of 3.8 nM.
CAS Number
2135922-40-4
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kδ-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@](C)(NCC(C)(F)C)C2=CC(C3=C4N=C(C5=CN=C(C)N=C5)N(CC)C4=NC=N3)=CN=C2N1
Molecular Formula
C24H26FN9O
Molecular Weight
475.52
References & Citations
[1]Methot JL, et al. Optimization of Versatile Oxindoles as Selective PI3Kδ Inhibitors. ACS Med Chem Lett. 2020 Nov 19;11 (12) :2461-2469.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported