Products for Research Use Only
RegisterLogin

PI3K-IN-6

CAT: 0804-HY-101115Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101115Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PI3K-IN-6 (compound 20a) is an oral active and highly selective phosphoinositide 3-kinase (PI3K) β/δ inhibitor, with IC50 values of 7.8 nM/5.3 nM for PI3K β/δ, respectively. PI3K-IN-6 (compound 20a) has potential top treat phosphatase and tensin homolog (PTEN) feficient tumors[1].
CAS Number
1842380-77-1
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3k-in-6.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(Cl)=C(N=C([C@@H](NC2=C(Cl)C(N)=NC(N)=N2)C)N(C3=NNC=C3)C4=O)C4=C1
Molecular Formula
C17H14Cl2FN9O
Molecular Weight
450.26
References & Citations
[1]Perreault S, et al. Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856. J Med Chem. 2017 Feb 23;60 (4) :1555-1567.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kδ

Related Products

CatalogName
HY-147613PI3K/mTOR Inhibitor-6
HY-179623PI3Kα-IN-29
HY-178984PI3Kα-IN-28
HY-178812PI3Kα-IN-27
HY-172886PI3K-IN-58
HY-172785PI3K-IN-57
HY-134472PI3Kδ-IN-8
HY-142677PI3K-IN-27
HY-136806PI3K-IN-12
HY-160282PI3K-IN-49

Alternative Products

CatalogName
T62073-01PI3Kα-IN-6
T12457-01PI3K-IN-6
A20687-100PI3K-IN-6 100mg
A20687-1PI3K-IN-6 1mg
A20687-25PI3K-IN-6 25mg
A20687-5PI3K-IN-6 5mg
T72613-01PI3Kγ inhibitor 6
A20687-50PI3K-IN-6 50mg
A20687-10PI3K-IN-6 10mg
GTR19184485-01PI3K/mTOR Inhibitor-6

Popular Products