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EGFR-IN-25

CAT: 0804-HY-142517Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142517Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-25 is a potent EGFR inhibitor with IC50s of 9 nM and 60 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and A431 cells (WT), respectively[1].
CAS Number
2749562-63-6
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-25.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC(C2=CC=CC3=C2C=CN3)=C(NC4CCOCC4)N=C1NC5=CC=C(N6CCC(N7CCN(C)CC7)CC6)C=C5)N
Molecular Formula
C34H43N9O2
Molecular Weight
609.76
References & Citations
[1]New pyrazine compound. WO2021244505A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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