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EGFR-IN-153

CAT: 0804-HY-173146Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173146Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-153 (Compound 5l) is an EGFR inhibitor. EGFR-IN-153 can inhibit the proliferation (IC50: 0.73 μM) and induce apoptosis of MDA-MB-231 cell. EGFR-IN-153 can be used for the research of breast cancer[1].
UNSPSC
12352005
Target
Apoptosis; EGFR
Related Pathways
Apoptosis; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
N#CC1CCCN1C(CN2C(/C(C3=C2C=CC(Cl)=C3)=N\NC4=NC=C(C5=CC=C(OC)C=C5)S4)=O)=O
Molecular Formula
C25H21ClN6O3S
Molecular Weight
520.99
References & Citations
[1]Alegaon SG, et al. Design, synthesis and molecular dynamics simulations of thiazole-based hydrazones targeting MDA-MB-231 breast cancer cells. Bioorg Chem. 2025 Apr;157:108306.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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