TCO-PEG6-NHS ester
CAT:
804-HY-141168
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TCO-PEG6-NHS ester
- CAS Number: 2353409-96-6
- UNSPSC Description: TCO-PEG6-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. TCO-PEG6-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tco-peg6-nhs-ester.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O
- Molecular Weight: 602.67
- References & Citations: [1]Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported