TCO-PEG2-NHS ester

• Description:

  TCO-PEG2-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG2-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  PROTAC Linkers

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Smiles:

  O=C(NCCOCCOCCC(ON1C(CCC1=O)=O)=O)OC2CC/C=C\CCC2

• Molecular Formula:

  C20H30N2O8

• Molecular Weight:

  426.46

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]https://pubchem.ncbi.nlm.nih.gov/#query=TCO-PEG5-NHS%20este

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; PEG Linkers

• CAS Number:

  [2250217-33-3]