WSPC Biotin-PEG3-DBCO

• UNSPSC Description:

  WSPC Biotin-PEG3-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. WSPC Biotin-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/wspc-biotin-peg3-dbco.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [H][C@]1(N2)CS[C@H]([C@@](NC2=O)1[H])CCCCC(NCCOCCOCCOCCNC(C(S(=O)(O)=O)CNC(CCCOC3=CC([N+]([O-])=O)=C(C(C)OC(NCCC(N4CC5=CC=CC=C5C#CC6=CC=CC=C64)=O)=O)C=C3OC)=O)=O)=O

• Molecular Weight:

  1153.28

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported