Propargyl-PEG1-SS-PEG1-PFP ester

Propargyl-PEG1-SS-PEG1-PFP ester

• CAS Number: 1817735-30-0
• UNSPSC Description: Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: ADC Linker
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/propargyl-peg1-ss-peg1-pfp-ester.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCSSCCOCC#C
• Molecular Weight: 430.41
• References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported