Propargyl-PEG1-SS-PEG1-PFP ester
CAT:
804-HY-140110
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Propargyl-PEG1-SS-PEG1-PFP ester
- CAS Number: 1817735-30-0
- UNSPSC Description: Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/propargyl-peg1-ss-peg1-pfp-ester.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCSSCCOCC#C
- Molecular Weight: 430.41
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported