Propargyl-PEG1-SS-PEG1-acid
CAT:
804-HY-140109-02
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Propargyl-PEG1-SS-PEG1-acid
- CAS Number: 1807503-85-0
- UNSPSC Description: Propargyl-PEG1-SS-PEG1-acid is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/propargyl-peg1-ss-peg1-acid.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(O)CCOCCSSCCOCC#C
- Molecular Weight: 264.36
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported