Anticancer agent 16

• Description:

  Anticancer agent 16 exhibits good cytotoxic activity against HCT-116, NCI-H460, and SKOV3 cell lines with IC50 8.55 μΜ, 5.41 μΜ, and 6.4 μΜ, respectively.

• UNSPSC:

  12352005

• Target:

  Apoptosis; Reactive Oxygen Species (ROS)

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)/C=C/CCCCC(NCC1=CC=C(OCC2=NN=C(NC3=CC=C([N+]([O-])=O)C=C3)O2)C(OC)=C1)=O

• Molecular Formula:

  C27H33N5O6

• Molecular Weight:

  523.58

• References & Citations:

  [1]Naaz F, et al. Apoptosis Inducing 1,3,4-Oxadiazole Conjugates of Capsaicin: Their In Vitro Antiproliferative and In Silico Studies. ACS Med Chem Lett. 2021 Oct 21;12 (11) :1694-1702.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2761205-38-1]