PARP1-IN-6
CAT:
804-HY-139879
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PARP1-IN-6
- CAS Number: 1654735-36-0
- UNSPSC Description: PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC50 values of 0.94 and 0.48 μM, respectively.
- Target Antigen: PARP
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/parp1-in-6.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1C2=CC=CC=C2N=C(/C=C/C3=CC(F)=CC=C3)N1
- Molecular Weight: 266.27
- References & Citations: [1]Zheng L, et al. Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation. J Med Chem. 2021 Nov 11;64(21):15702-15715.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported