PARP1-IN-6

PARP1-IN-6

• CAS Number: 1654735-36-0
• UNSPSC Description: PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC50 values of 0.94 and 0.48 μM, respectively.
• Target Antigen: PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/parp1-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=CC=CC=C2N=C(/C=C/C3=CC(F)=CC=C3)N1
• Molecular Weight: 266.27
• References & Citations: [1]Zheng L, et al. Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation. J Med Chem. 2021 Nov 11;64(21):15702-15715.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported