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PARP1-IN-6

CAT: 0804-HY-139879Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139879Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC50 values of 0.94 and 0.48 μM, respectively.
CAS Number
1654735-36-0
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp1-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC=CC=C2N=C(/C=C/C3=CC(F)=CC=C3)N1
Molecular Formula
C16H11FN2O
Molecular Weight
266.27
References & Citations
[1]Zheng L, et al. Discovery of a Dual Tubulin and Poly (ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation. J Med Chem. 2021 Nov 11;64 (21) :15702-15715.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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