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PARP1-IN-45

CAT: 0804-HY-178100Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178100Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1-IN-45 (Compound 15) is a PARP1 inhibitor with an IC50 of 17 nM. PARP1-IN-45 effectively stimulates ATPase activity of ABCG2. PARP1-IN-45 can be used for cancers like ovarian cancer research[1].
UNSPSC
12352005
Target
BCRP; PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
NC(C1=CC=CC2=C1O/C(C2=O)=C\C3=CC=C(C(N4CCN(CC4)C5=NC6=C(N5)C=CC=C6)=O)S3)=O
Molecular Formula
C26H21N5O4S
Molecular Weight
499.54
References & Citations
[1]Salami A, et al. Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors. Bioorg Chem. 2025 Sep 5;165:108941.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1

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