Anti-inflammatory agent 7

• UNSPSC Description:

  Anti-inflammatory agent 7 inhibits proinflammatory cytokines by blocking the NF-κB/MAPK signaling pathway in LPS-treated RAW 264.7 cells as well as mice.

• Target Antigen:

  NF-κB; p38 MAPK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway;NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/anti-inflammatory-agent-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1[C@@H]2[C@]3(O2)[C@@]4(C)[C@]([C@]([C@@](C5)([H])OC6(C)C)(COC5=O)[C@@]6([H])C/C4=N\OCC7=CN(C8=CC=C(OC)C=C8)N=N7)([H])CC[C@@]3(C)[C@H](C9=COC=C9)O1

• Molecular Weight:

  672.72

• References & Citations:

  [1]Bian M, et al. Design, Synthesis, and In Vitro and In Vivo Biological Evaluation of Limonin Derivatives for Anti-Inflammation Therapy. J Agric Food Chem. 2021 Nov 17;69(45):13487-13499.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4