Anti-inflammatory agent 7

CAT: 0804-HY-139844Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-139844Size:1 Each
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Description
Anti-inflammatory agent 7 inhibits proinflammatory cytokines by blocking the NF-κB/MAPK signaling pathway in LPS-treated RAW 264.7 cells as well as mice.
CAS Number
[2759194-24-4]
UNSPSC
12352005
Target
NF-κB; p38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-7.html
Solubility
10 mM in DMSO
Smiles
O=C1[C@@H]2[C@]3(O2)[C@@]4(C)[C@]([C@]([C@@](C5)([H])OC6(C)C)(COC5=O)[C@@]6([H])C/C4=N\OCC7=CN(C8=CC=C(OC)C=C8)N=N7)([H])CC[C@@]3(C)[C@H](C9=COC=C9)O1
Molecular Formula
C36H40N4O9
Molecular Weight
672.72
References & Citations
[1]Bian M, et al. Design, Synthesis, and In Vitro and In Vivo Biological Evaluation of Limonin Derivatives for Anti-Inflammation Therapy. J Agric Food Chem. 2021 Nov 17;69 (45) :13487-13499.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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