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MCX 28

CAT: 0804-HY-139832Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139832Size:1 Each
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Description
MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.
CAS Number
1414453-58-9
UNSPSC
12352005
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcx-28.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=CN=C(OC)C(NS3(=O)=O)=C2)SC4=C1N=CN=C4C5=CC=C(CNC(C6=CC3=CC=C6)=O)S5
Molecular Formula
C25H19N5O4S3
Molecular Weight
549.64
References & Citations
[1]Martínez-González S, et al. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12 (11) :1794-1801.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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