Dovitinib (dilactic acid)

CAT: 0804-HY-13892Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-13892Size:1 Each
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Description
Dovitinib (dilactic acid) is an orally active inhibitor of VEGF kinase. Dovitinib (dilactic acid) inhibits receptor tyrosine kinases (RTKs) involved in solid and hematologic cancers and tumor angiogenesis[1].
CAS Number
[852433-84-2]
Product Name Alternative
CHIR-258 (dilactic acid) ; TKI258 (dilactic acid)
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dovitinib-dilactic-acid.html
Solubility
DMSO : ≥ 30 mg/mL
Smiles
CC(O)C(O)=O.CC(O)C(O)=O.O=C1NC2=C(C(F)=CC=C2)C(N)=C1C3=NC4=CC=C(N5CCN(C)CC5)C=C4N3
Molecular Formula
C27H33FN6O7
Molecular Weight
572.59
References & Citations
[1]Zhu, S., et al. The Chemical Development of CHIR-258. CHIMIA International Journal for Chemistry, 60 (9), 584–592.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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