Products for Research Use Only
RegisterLogin

2-Hydroxy atorvastatin lactone

CAT: 0804-HY-136346Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-136346Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
CAS Number
163217-74-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2-hydroxy-atorvastatin-lactone.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(C)C)N(CC[C@@H]2C[C@@H](O)CC(O2)=O)C(C3=CC=C(F)C=C3)=C1C4=CC=CC=C4)NC5=CC=CC=C5O
Molecular Formula
C33H33FN2O5
Molecular Weight
556.62
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42 (8) :784‐790.|[2]Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. J Cardiovasc Pharmacol. 2007 Oct;50 (4) :458-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-1268524-Hydroxy Atorvastatin lactone
HY-136346S-01Ortho-hydroxy atorvastatin lactone-d5
HY-126852S4-Hydroxy Atorvastatin lactone-d5
HY-101873-01Atorvastatin lactone
HY-101873R-01Atorvastatin lactone (Standard)
HY-101873S-01Atorvastatin lactone-d5
HY-143840S-012-Hydroxy Atorvastatin-d5 (disodium)
HY-128828-012-Hydroxy atorvastatin (calcium salt)
HY-141987S12-Hydroxy atorvastatin sodium salt-d5
HY-137310-014-Hydroxy atorvastatin (hemicalcium)

Alternative Products

CatalogName
FH23908-012-Hydroxy atorvastatin lactone
RM-A202230-01Atorvastatin 2-Hydroxy Lactone
TRC-H828957-1MG2-Hydroxy Atorvastatin Lactone-d5
FH23909-014-Hydroxy atorvastatin lactone
RM-A202232-01Atorvastatin 4-Hydroxy Lactone
MBS6018749-01p-Hydroxy Atorvastatin Lactone
AR-A02779-01Ortho-Hydroxy Atorvastatin Lactone
MBS6019991-01o-Hydroxy Atorvastatin Lactone
AR-A02778-01Para-Hydroxy Atorvastatin Lactone

Popular Products