RegisterLogin

Deruxtecan-d5

CAT: 0804-HY-13631ES4-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-13631ES4-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Deruxtecan-d5 is deuterium labeled Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
Product Name Alternative
MC-GGFG-DXD-d5
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Antibody-drug Conjugate/ADC Related; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.40
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)C([2H])([2H])C([2H])([2H])[2H])=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
Molecular Formula
C52H51D5FN9O13
Molecular Weight
1039.08
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1.|[3]Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107 (7) :1039-46.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-153891SDeruxtecan 2-hydroxypropanamide-d5
HY-13631E-01Deruxtecan
HY-13631ES1-01Deruxtecan-d6
HY-13631EG-01Deruxtecan (GMP)
HY-164734-01Raludotatug Deruxtecan
HY-141598-01Datopotamab deruxtecan
HY-138298A-01Trastuzumab deruxtecan
HY-P99813-01Patritumab deruxtecan
HY-164835-01VcMMAE-Deruxtecan
HY-13631O-01(1R) -Deruxtecan

Alternative Products

CatalogName
M26662-01Deruxtecan
M34869-01Trastuzumab deruxtecan
T9901A-091-01Ifinatamab deruxtecan
MBS5825225(1R)-Deruxtecan
A21522-25Deruxtecan 25mg
C00965-01Patritumab deruxtecan
C00993-01Datopotamab deruxtecan
T83576-01(1R) -Deruxtecan
A21522-10Deruxtecan 10mg
T201614-01VcMMAE-Deruxtecan

Popular Products