Deruxtecan-d2

• Description :

  Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E) [1]. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

• Product Name Alternative :

  MC-GGFG-DXD-d2

• UNSPSC :

  12352005

• Target :

  Drug-Linker Conjugates for ADC; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Others

• Field of Research :

  Others

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOC([2H])([2H])C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C52H54D2FN9O13

• Molecular Weight :

  1036.06

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [2760715-87-3]