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VcMMAE-Deruxtecan

CAT: 0804-HY-164835-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-164835-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VcMMAE-Deruxtecan (SMP-54418) is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule MMAE (Microtubule inhibitor) and Exatecan (HY-13631) (DNA topoisomerase I inhibitor). VcMMAE-Deruxtecan can be used for ADC synthesis.
CAS Number
2760408-75-9
Product Name Alternative
SMP-54418
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Microtubule/Tubulin; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vcmmae-deruxtecan.html
Purity
98.10
Solubility
DMSO : 50 mg/mL
Smiles
CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(C(NC(CCCCCN4C(C=CC4=O)=O)=O)CC(C=C5)=CC=C5OCC(NCC(NCC(N[C@@H](CC6=CC=CC=C6)C(NCC(NCOCC(N[C@@H]7C8=C9C(C(N%10C9)=CC([C@](O)(C(OC%11)=O)CC)=C%11C%10=O)=NC%12=CC(F)=C(C)C(CC7)=C%128)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C121H159FN20O28
Molecular Weight
2360.67
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Dual payloads; Topo I

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