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Amphotericin X1

CAT: 0804-HY-136153-01Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-136153-01Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and A.fumigatus with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively[1].
CAS Number
136135-57-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/amphotericin-x1.html
Solubility
10 mM in DMSO
Smiles
CO[C@](C[C@@H]1O)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(O[C@H]([C@@H]([C@@H]2O)C)C)=O)O)O)O)O)O)O[C@](C[C@H](/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H]2C)O[C@@](O[C@@H]3C)([H])[C@H]([C@H]([C@@H]3O)N)O)([H])[C@@H]1C(O)=O
Molecular Formula
C48H75NO17
Molecular Weight
938.11
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Taylor AW, et al. Synthesis and antifungal selectivity of new derivatives of amphotericin B modified at the C-13 position. J Antibiot (Tokyo) . 1993 Mar;46 (3) :486-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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