Dihydro Dutasteride

• Description :

  Dihydro Dutasteride is a metabolite of Dutasteride. Dutasteride is a potent inhibitor of both 5 alpha-reductase isozymes[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H351, H360

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/dihydro-dutasteride.html

• Purity :

  99.72

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C([C@H]1CC[C@]2([H])[C@]1(C)CC[C@]3([H])[C@@]4(C)CCC(N[C@]4([H])CC[C@]32[H])=O)NC5=CC(C(F)(F)F)=CC=C5C(F)(F)F

• Molecular Formula :

  C27H32F6N2O2

• Molecular Weight :

  530.55

• Precautions :

  H351, H360

• References & Citations :

  [1] Lazier CB, et al. Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line. Prostate. 2004 Feb 1;58 (2) :130-44.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [164656-22-8]