Kinetin triphosphate

Kinetin triphosphate

• CAS Number: 1450894-16-2
• UNSPSC Description: Kinetin triphosphate(6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research[1].
• Target Antigen: PINK1/Parkin
• Type: Reference compound
• Related Pathways: Autophagy;Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/kinetin-triphosphate.html
• Solubility: 10 mM in DMSO
• Smiles: O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O
• Molecular Weight: 587.27
• References & Citations: [1]Nicholas T Hertz, et al. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 2013 Aug 15;154(4):737-47.
• Shipping Conditions: Room temperature
• Clinical Information: Phase 4