Kinetin triphosphate

• UNSPSC Description:

  Kinetin triphosphate(6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research[1].

• Target Antigen:

  PINK1/Parkin

• Type:

  Reference compound

• Related Pathways:

  Autophagy;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/kinetin-triphosphate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O

• Molecular Weight:

  587.27

• References & Citations:

  [1]Nicholas T Hertz, et al. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 2013 Aug 15;154(4):737-47.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 4

• CAS Number:

  1450894-16-2