14-Norpseurotin

• Description:

  14-Norpseurotin is a compound isolated from the culture of Aspergillus fumigatus. 14-Norpseurotin significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/14-norpseurotin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1)[C@@](OC([C@@H](O)[C@@H](O)/C=C\C)=C2C)(C2=O)[C@@H](O)[C@]1(OC)C(C3=CC=CC=C3)=O

• Molecular Formula:

  C21H23NO8

• Molecular Weight:

  417.41

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1] Ge HM, et al. Bioactive alkaloids from endophytic Aspergillus fumigatus. J Nat Prod. 2009;72 (4) :753-755.|[2]Bonday ZQ, et al. LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med Chem Lett. 2018;9 (7) :612-617.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [1031727-34-0]