MNK/PIM-IN-1

MNK/PIM-IN-1

• CAS Number: 2430792-91-7
• UNSPSC Description: MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile.
• Target Antigen: Pim
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mnk-pim-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C(C2=NC3=C(NC4=CC=C(F)C=C4OC(C)C)N=CN=C3C=C2)C=C1)N5CCNCC5
• Molecular Weight: 486.54
• References & Citations: [1]Han Y, et al. Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth. J Med Chem. 2021 Sep 23;64(18):13719-13735.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported