MNK/PIM-IN-1

• UNSPSC Description:

  MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile.

• Target Antigen:

  Pim

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mnk-pim-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C2=NC3=C(NC4=CC=C(F)C=C4OC(C)C)N=CN=C3C=C2)C=C1)N5CCNCC5

• Molecular Weight:

  486.54

• References & Citations:

  [1]Han Y, et al. Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth. J Med Chem. 2021 Sep 23;64(18):13719-13735.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2430792-91-7