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PIM-IN-1

CAT: 0804-HY-142656Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-142656Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM) .
CAS Number
2698319-19-4
UNSPSC
12352005
Target
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Cl)=C2C(N([C@H]([C@@]3(F)CNCC3)C)C=C2C)=N1)N
Molecular Formula
C15H18ClFN4O
Molecular Weight
324.78
References & Citations
[1]Barberis C, et al. Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model. Bioorg Med Chem Lett. 2020 Dec 1;30 (23) :127625.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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