RG-101

• Description :

  RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].

• Product Name Alternative :

  Temavirsen

• UNSPSC :

  12352208

• Target :

  HCV; MicroRNA

• Type :

  Oligonucleotides

• Related Pathways :

  Anti-infection; Epigenetics

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/rg-101.html

• Solubility :

  10 mM in H2O

• Smiles :

  [RG-101]

• Molecular Formula :

  C295H410N78Na19O146P19S17

• Molecular Weight :

  8537.6

• References & Citations :

  [1]Meike H van der Ree, et al. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial. Lancet. 2017 Feb 18;389 (10070) :709-717.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Oligonucleotides

• Clinical Information :

  No Development Reported

• CAS Number :

  [1929655-04-8]