RG-101

• Description:

  RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].

• Product Name Alternative:

  Temavirsen

• UNSPSC:

  12352208

• Target:

  HCV; MicroRNA

• Type:

  Oligonucleotides

• Related Pathways:

  Anti-infection; Epigenetics

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/rg-101.html

• Solubility:

  10 mM in H2O

• Smiles:

  [RG-101]

• Molecular Formula:

  C295H410N78Na19O146P19S17

• Molecular Weight:

  8537.6

• References & Citations:

  [1]Meike H van der Ree, et al. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial. Lancet. 2017 Feb 18;389 (10070) :709-717.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Oligonucleotides

• Clinical Information:

  No Development Reported

• CAS Number:

  [1929655-04-8]