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RG-12525

CAT: 0931-T16739-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16739-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
120128-20-3
Target
PPAR, Cytochromes P450, Leukotriene Receptor
Related Pathways
Metabolism, GPCR/G Protein, DNA Damage/DNA Repair
Purity
0.9677
Bioactivity
RG-12525 (NID 525) is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guinea pig thin-walled bands, with IC50 values of 2.6 nM, 2.5 nM, and 7 nM, respectively.RG-12525 inhibits CYP3A4, with a Ki value of 0.5 μM. RG-12525 is a novel and potent PPAR-γ agonist (IC50 value of about 60 nM) with species specificity for the study of asthma.
Smiles
N1=NNC(=N1)CC=2C=CC=CC2COC3=CC=C(OCC4=NC=5C=CC=CC5C=C4)C=C3
Molecular Formula
C25H21N5O2
Molecular Weight
423.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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BA4464-5.1RG-12525
A19926-10RG-12525 10mg
A19926-50RG-12525 50mg
HY-101676RRG-12525 (Standard)
A19926-1RG-12525 1mg
A19926-100RG-12525 100mg
A19926-25RG-12525 25mg
A19926-5RG-12525 5mg
A19926-2RG-12525 2mg
A1913-25RG 108

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